FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NF-YA
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
43kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NFYA. AA range:261-310
特异性
NF-YA Polyclonal Antibody detects endogenous levels of NF-YA protein.
基因名称
NFYA
蛋白名称
Nuclear transcription factor Y subunit alpha
别名
NFYA;Nuclear transcription factor Y subunit alpha;CAAT box DNA-binding protein subunit A;Nuclear transcription factor Y subunit A;NF-YA
Organism-1
Human
基因ID-1
4800
SwissProt-1
P23511
Organism-2
Mouse
基因ID-2
18044
SwissProt-2
P23708
Organism-3
Rat
基因ID-3
29508
SwissProt-3
P18576
背景
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus.
