- 产品信息
商品描述
靶点-Target
NFATc2IP
反应性
Human,Rat,Mouse,Fish
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
48kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NFATC2IP. AA range:151-200
特异性
NFATc2IP Polyclonal Antibody detects endogenous levels of NFATc2IP protein.
基因名称
NFATC2IP
蛋白名称
NFATC2-interacting protein
别名
NFATC2IP;NIP45;NFATC2-interacting protein;45 kDa NF-AT-interacting protein;45 kDa NFAT-interacting protein;Nuclear factor of activated T-cells;cytoplasmic 2-interacting protein
Organism-1
Human
基因ID-1
84901
SwissProt-1
Q8NCF5
Organism-2
Mouse
SwissProt-2
O09130
背景
function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production.,PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus.,subunit:Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.,
细胞定位
Nucleus . Cytoplasm . TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. .





