Neurofibromin Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2615191
- 产品信息
商品描述
靶点-Target
Neurofibromin
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
319kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NF1. AA range:1551-1600
特异性
Neurofibromin Polyclonal Antibody detects endogenous levels of Neurofibromin protein.
基因名称
NF1
蛋白名称
Neurofibromin
别名
NF1;Neurofibromin;Neurofibromatosis-related protein NF-1
Organism-1
Human
基因ID-1
4763
SwissProt-1
P21359
Organism-2
Mouse
基因ID-2
18015
SwissProt-2
Q04690
Organism-3
Rat
基因ID-3
24592
SwissProt-3
P97526
背景
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Nucleus, nucleolus .





