Neurofibromin Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615191

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商品描述
  • 靶点-Target

    Neurofibromin

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    319kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human NF1. AA range:1551-1600

  • 特异性

    Neurofibromin Polyclonal Antibody detects endogenous levels of Neurofibromin protein.

  • 基因名称

    NF1

  • 蛋白名称

    Neurofibromin

  • 别名

    NF1;Neurofibromin;Neurofibromatosis-related protein NF-1

  • Organism-1

    Human

  • 基因ID-1

    4763

  • SwissProt-1

    P21359

  • Organism-2

    Mouse

  • 基因ID-2

    18015

  • SwissProt-2

    Q04690

  • Organism-3

    Rat

  • 基因ID-3

    24592

  • SwissProt-3

    P97526

  • 背景

    This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Nucleus . Nucleus, nucleolus .