Neurexin IIIβ Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615183

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商品描述
  • 靶点-Target

    Neurexin IIIβ

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,ELISA,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    70kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from Neurexin IIIβ . at AA range: 30-110

  • 特异性

    Neurexin IIIβ Polyclonal Antibody detects endogenous levels of Neurexin IIIβ protein.

  • 基因名称

    NRXN3

  • 蛋白名称

    Neurexin-3-beta

  • 别名

    NRXN3;KIAA0743;Neurexin-3-beta;Neurexin III-beta

  • Organism-1

    Human

  • 基因ID-1

    9369

  • SwissProt-1

    Q9HDB5

  • Organism-2

    Mouse

  • SwissProt-2

    Q8C985

  • 背景

    NRXN3 (neurexin 3) encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder.

  • 细胞定位

    Membrane ; Single-pass type I membrane protein .