FGF-2 Polyclonal Antibody
¥680.00
Neurexin I Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2615182
- 产品信息
商品描述
靶点-Target
Neurexin I
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
150kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NRXN1. AA range:502-551
特异性
Neurexin I Polyclonal Antibody detects endogenous levels of Neurexin I protein.
基因名称
NRXN1
蛋白名称
Neurexin-1-alpha
别名
NRXN1;KIAA0578;Neurexin-1-alpha;Neurexin I-alpha
Organism-1
Human
基因ID-1
9378
SwissProt-1
Q9ULB1
Organism-2
Mouse
基因ID-2
18189
SwissProt-2
Q9CS84
Organism-3
Rat
基因ID-3
60391
SwissProt-3
Q63372
背景
NRXN1 (neurexin 1) encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for NRXN1 in the 3' region. Mutations in NRXN1 are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.
细胞定位
Cell junction, synapse, presynaptic cell membrane ; Single-pass type I membrane protein .
