FGF-2 Polyclonal Antibody
¥680.00
Nephrocystin-5 Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2615171
- 产品信息
商品描述
靶点-Target
Nephrocystin-5
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
69kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human IQCB1. AA range:431-480
特异性
Nephrocystin-5 Polyclonal Antibody detects endogenous levels of Nephrocystin-5 protein.
基因名称
IQCB1
蛋白名称
IQ calmodulin-binding motif-containing protein 1
别名
IQCB1;KIAA0036;NPHP5;OK/SW-cl.85;IQ calmodulin-binding motif-containing protein 1;Nephrocystin-5;p53 and DNA damage-regulated IQ motif protein;PIQ
Organism-1
Human
基因ID-1
9657
SwissProt-1
Q15051
Organism-2
Mouse
SwissProt-2
Q8BP00
背景
This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Jan 2016],
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Localization to the centrosome depends on the interaction with CEP290/NPHP6.
