FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NEIL3
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
68kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NEIL3. AA range:491-540
特异性
NEIL3 Polyclonal Antibody detects endogenous levels of NEIL3 protein.
基因名称
NEIL3
蛋白名称
Endonuclease 8-like 3
别名
NEIL3;Endonuclease 8-like 3;DNA glycosylase FPG2;DNA glycosylase/AP lyase Neil3;Endonuclease VIII-like 3;Nei-like protein 3
Organism-1
Human
基因ID-1
55247
SwissProt-1
Q8TAT5
Organism-2
Mouse
基因ID-2
234258
SwissProt-2
Q8K203
背景
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008],
细胞定位
Nucleus . Chromosome . Recruited to replication stress sites via interaction with ubiquitinated CMG helicase. .
