- 产品信息
商品描述
靶点-Target
Nck-2
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
43kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NCK2. AA range:331-380
特异性
Nck-2 Polyclonal Antibody detects endogenous levels of Nck-2 protein.
基因名称
NCK2
蛋白名称
Cytoplasmic protein NCK2
别名
NCK2;GRB4;Cytoplasmic protein NCK2;Growth factor receptor-bound protein 4;NCK adaptor protein 2;Nck-2;SH2/SH3 adaptor protein NCK-beta
Organism-1
Human
基因ID-1
8440
SwissProt-1
O43639
Organism-2
Mouse
基因ID-2
17974
SwissProt-2
O55033
背景
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Endoplasmic reticulum .





