NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2615118
- 产品信息
商品描述
靶点-Target
NBPF1/9/10/12/14/15/16/20
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
36kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NBPF1/9/10/12/14/15/16/20. AA range:121-150
特异性
NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody detects endogenous levels of NBPF1/9/10/12/14/15/16/20 protein.
基因名称
NBPF12
蛋白名称
Neuroblastoma breakpoint family member 12
别名
NBPF12;COAS1;KIAA1245;Neuroblastoma breakpoint family member 12;Chromosome 1 amplified sequence 1;NBPF10;Neuroblastoma breakpoint family member 10;NBPF16;Neuroblastoma breakpoint family member 16;NBPF1;KIAA1693;Neuroblastoma brea
Organism-1
Human
基因ID-1
55672;400818;284565;25832
SwissProt-1
Q5TAG4;Q6P3W6;Q5SXJ2;Q3BBV0;Q3BBW0;Q3BBV1;Q8N660;Q5TI25
背景
This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This
细胞定位
Cytoplasm .





