FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NAB2
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
56kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NAB2. AA range:261-310
特异性
NAB2 Polyclonal Antibody detects endogenous levels of NAB2 protein.
基因名称
NAB2
蛋白名称
NGFI-A-binding protein 2
别名
NAB2;MADER;NGFI-A-binding protein 2;EGR-1-binding protein 2;Melanoma-associated delayed early response protein;Protein MADER
Organism-1
Human
基因ID-1
4665
SwissProt-1
Q15742
Organism-2
Mouse
基因ID-2
17937
SwissProt-2
Q61127
背景
This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Isoform 2 is not localized to the nucleus. .
