Na+/K+-ATPase α2 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2615108
- 产品信息
商品描述
靶点-Target
Na+/K+-ATPase α2
反应性
Human,Mouse,Rat,Monkey
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
112kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ATP1A2. AA range:971-1020
特异性
Na+/K+-ATPase α2 Polyclonal Antibody detects endogenous levels of Na+/K+-ATPase α2 protein.
基因名称
ATP1A2
蛋白名称
Sodium/potassium-transporting ATPase subunit alpha-2
别名
ATP1A2;KIAA0778;Sodium/potassium-transporting ATPase subunit alpha-2;Na;+;/K;+;ATPase alpha-2 subunit;Sodium pump subunit alpha-2
Organism-1
Human
基因ID-1
477
SwissProt-1
P50993
Organism-2
Mouse
基因ID-2
98660
SwissProt-2
Q6PIE5
Organism-3
Rat
基因ID-3
24212
SwissProt-3
P06686
背景
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008],
细胞定位
Membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .





