Na+ CP-pan Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2615106
- 产品信息
商品描述
靶点-Target
Na+ CP-pan
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
230kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Sodium Channel. AA range:1466-1515
特异性
Na+ CP-pan Polyclonal Antibody detects endogenous levels of Na+ CP-pan protein.
基因名称
SCN1A/SCN2A/SCN3A/SCN4A/SCN5A/SCN8A/SCN9A/SCN10A/SCN11A
蛋白名称
Sodium channel protein type 1 subunit alpha
别名
SCN1A;NAC1;SCN1;Sodium channel protein type 1 subunit alpha;Sodium channel protein brain I subunit alpha;Sodium channel protein type I subunit alpha;Voltage-gated sodium channel subunit alpha Nav1.1;SCN2A;NAC2;SCN2A1;SCN2A2;Sodiu
Organism-1
Human
基因ID-1
6323;6326;6328;6329;6331;6334;6335;6336;11280
SwissProt-1
P35498;Q99250;Q9NY46;P35499;Q14524;Q9UQD0;Q15858;Q9Y5Y9;Q9UI33
Organism-2
Mouse
基因ID-2
110880
Organism-3
Rat
基因ID-3
81574;24766;497770;25722
SwissProt-3
P04774;P04775;P08104;P15390
背景
Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits. This gene encodes a sodium channel alpha subunit, which has four homologous domains, each of which contains six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, th
细胞定位
Cell membrane ; Multi-pass membrane protein .





