Na+ CP type VIIα Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615105

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商品描述
  • 靶点-Target

    Na+ CP type VIIα

  • 反应性

    Human,Monkey

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    200kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human SCN7A. AA range:771-820

  • 特异性

    Na+ CP type VIIα Polyclonal Antibody detects endogenous levels of Na+ CP type VIIα protein.

  • 基因名称

    SCN7A

  • 蛋白名称

    Sodium channel protein type 7 subunit alpha

  • 别名

    SCN7A;SCN6A;Sodium channel protein type 7 subunit alpha;Putative voltage-gated sodium channel subunit alpha Nax;Sodium channel protein cardiac and skeletal muscle subunit alpha;Sodium channel protein type VII subunit alpha

  • Organism-1

    Human

  • 基因ID-1

    6332

  • SwissProt-1

    Q01118

  • 背景

    This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011],

  • 细胞定位

    Cell membrane ; Multi-pass membrane protein .