FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MYPT3
反应性
Human,Mouse
应用
WB,IF,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-2000;IF/ICC1:50-200;ELISA 1:2000-20000;IHC 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PPP1R16A. AA range:362-411
特异性
MYPT3 Polyclonal Antibody detects endogenous levels of MYPT3 protein.
基因名称
PPP1R16A
蛋白名称
Protein phosphatase 1 regulatory subunit 16A
别名
PPP1R16A;MYPT3;Protein phosphatase 1 regulatory subunit 16A;Myosin phosphatase-targeting subunit 3
Organism-1
Human
基因ID-1
84988
SwissProt-1
Q96I34
Organism-2
Mouse
SwissProt-2
Q923M0
背景
Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c. [provided by RefSeq, Jul 2016],
细胞定位
Cell membrane ; Lipid-anchor .
