Myosin VA Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2615089
- 产品信息
商品描述
靶点-Target
Myosin VA
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
220kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MYO5A. AA range:1784-1833
特异性
Myosin VA Polyclonal Antibody detects endogenous levels of Myosin VA protein.
基因名称
MYO5A
蛋白名称
Unconventional myosin-Va
别名
MYO5A;MYH12;Unconventional myosin-Va;Dilute myosin heavy chain;non-muscle;Myosin heavy chain 12;Myosin-12;Myoxin
Organism-1
Human
基因ID-1
4644
SwissProt-1
Q9Y4I1
Organism-2
Mouse
基因ID-2
17918
SwissProt-2
Q99104
Organism-3
Rat
基因ID-3
25017
SwissProt-3
Q9QYF3
背景
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined. [provided by RefSeq, Dec 2008],
细胞定位
ruffle,photoreceptor outer segment,cytoplasm,lysosome,early endosome,late endosome,peroxisome,endoplasmic reticulum,Golgi apparatus,cytosol,intermediate filament,actin filament,membrane,myosin complex,gr





