Myomesin-1 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2615085
- 产品信息
商品描述
靶点-Target
Myomesin-1
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
162kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MYOM1. AA range:824-873
特异性
Myomesin-1 Polyclonal Antibody detects endogenous levels of Myomesin-1 protein.
基因名称
MYOM1
蛋白名称
Myomesin-1
别名
MYOM1;Myomesin-1;190 kDa connectin-associated protein;190 kDa titin-associated protein;Myomesin family member 1
Organism-1
Human
基因ID-1
8736
SwissProt-1
P52179
Organism-2
Mouse
SwissProt-2
Q62234
背景
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure
细胞定位
Cytoplasm, myofibril, sarcomere, M line .





