- 产品信息
商品描述
靶点-Target
MYH
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MUTYH. AA range:151-200
特异性
MYH Polyclonal Antibody detects endogenous levels of MYH protein.
基因名称
MUTYH
蛋白名称
A/G-specific adenine DNA glycosylase
别名
MUTYH;MYH;A/G-specific adenine DNA glycosylase;MutY homolog;hMYH
Organism-1
Human
基因ID-1
4595
SwissProt-1
Q9UIF7
Organism-2
Mouse
基因ID-2
70603
SwissProt-2
Q99P21
Organism-3
Rat
基因ID-3
170841
SwissProt-3
Q8R5G2
背景
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Mitochondrion .





