FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MyD88
反应性
Human,Mouse,Rat,Pig
应用
IF,WB,IHC,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
33kD
推荐稀释比
IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;ICC 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MyD88. AA range:171-220
特异性
MyD88 Polyclonal Antibody detects endogenous levels of MyD88 protein.
基因名称
MyD88
蛋白名称
Myeloid differentiation primary response protein MyD88
别名
MYD88;Myeloid differentiation primary response protein MyD88
Organism-1
Human
基因ID-1
4615
SwissProt-1
Q99836
Organism-2
Mouse
基因ID-2
17874
SwissProt-2
P22366
Organism-3
Rat
基因ID-3
301059
SwissProt-3
Q6Y1S1
背景
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
细胞定位
Cytoplasm . Nucleus .
