- 产品信息
商品描述
靶点-Target
MRP-L40
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
24kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MRPL40. AA range:101-150
特异性
MRP-L40 Polyclonal Antibody detects endogenous levels of MRP-L40 protein.
基因名称
MRPL40
蛋白名称
39S ribosomal protein L40 mitochondrial
别名
MRPL40;NLVCF;URIM;39S ribosomal protein L40;mitochondrial;L40mt;MRP-L40;Nuclear localization signal-containing protein deleted in velocardiofacial syndrome;Up-regulated in metastasis
Organism-1
Human
基因ID-1
64976
SwissProt-1
Q9NQ50
Organism-2
Mouse
SwissProt-2
Q9Z2Q5
背景
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion .





