- 产品信息
商品描述
靶点-Target
MRP-L10
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
29kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MRPL10. AA range:211-260
特异性
MRP-L10 Polyclonal Antibody detects endogenous levels of MRP-L10 protein.
基因名称
MRPL10
蛋白名称
39S ribosomal protein L10 mitochondrial
别名
MRPL10;MRPL8;RPML8;39S ribosomal protein L10;mitochondrial;L10mt;MRP-L10;39S ribosomal protein L8, mitochondrial;L8mt;MRP-L8
Organism-1
Human
基因ID-1
124995
SwissProt-1
Q7Z7H8
Organism-2
Mouse
SwissProt-2
Q3TBW2
背景
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Nov 2010],
细胞定位
Mitochondrion .





