- 产品信息
商品描述
靶点-Target
MRP3
反应性
Human,Rat,Mouse,
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
170kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ABCC3. AA range:971-1020
特异性
MRP3 Polyclonal Antibody detects endogenous levels of MRP3 protein.
基因名称
ABCC3
蛋白名称
Canalicular multispecific organic anion transporter 2
别名
ABCC3;CMOAT2;MLP2;MRP3;Canalicular multispecific organic anion transporter 2;ATP-binding cassette sub-family C member 3;Multi-specific organic anion transporter D;MOAT-D;Multidrug resistance-associated protein 3
Organism-1
Human
基因ID-1
8714
SwissProt-1
O15438
Organism-2
Mouse
SwissProt-2
B2RX12
背景
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008],
细胞定位
Basolateral cell membrane ; Multi-pass membrane protein .





