- 产品信息
商品描述
靶点-Target
MRGX1
反应性
Human,Rat,Mouse,
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
36kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MRGX1. AA range:271-320
特异性
MRGX1 Polyclonal Antibody detects endogenous levels of MRGX1 protein.
基因名称
MRGPRX1
蛋白名称
Mas-related G-protein coupled receptor member X1
别名
MRGPRX1;MRGX1;SNSR3;SNSR4;Mas-related G-protein coupled receptor member X1;Sensory neuron-specific G-protein coupled receptor 3/4
Organism-1
Human
基因ID-1
259249
SwissProt-1
Q96LB2
Organism-2
Mouse
SwissProt-2
Q8CIP3
背景
function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,
细胞定位
Cell membrane; Multi-pass membrane protein.





