Moesin/Ezrin/Radixin Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614970

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商品描述
  • 靶点-Target

    Moesin/Ezrin/Radixin

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    67kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Moesin/Ezrin/Radixin. AA range:524-573

  • 特异性

    Moesin/Ezrin/Radixin Polyclonal Antibody detects endogenous levels of Moesin/Ezrin/Radixin protein.

  • 基因名称

    MSN

  • 蛋白名称

    Moesin

  • 别名

    MSN;Moesin;Membrane-organizing extension spike protein;RDX;Radixin;EZR;VIL2;Ezrin;Cytovillin;Villin-2;p81

  • Organism-1

    Human

  • 基因ID-1

    4478;5962

  • SwissProt-1

    P26038;P35241;P15311

  • Organism-2

    Mouse

  • 基因ID-2

    17698;19684;22350

  • Organism-3

    Rat

  • 基因ID-3

    81521;54319

  • SwissProt-3

    O35763;P31977

  • 背景

    Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton . Apical cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, microvillus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, microvillus . Phosphorylated form is enriched in microvilli-like structures at apical membrane. Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment (By similarity). Localizes at the uropods of T lymphoblasts. .