- 产品信息
商品描述
靶点-Target
MNT
反应性
Human,Mouse
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
62kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MNT. AA range:315-364
特异性
MNT Polyclonal Antibody detects endogenous levels of MNT protein.
基因名称
MNT
蛋白名称
Max-binding protein MNT
别名
MNT;BHLHD3;ROX;Max-binding protein MNT;Class D basic helix-loop-helix protein 3;bHLHd3;Myc antagonist MNT;Protein ROX
Organism-1
Human
基因ID-1
4335
SwissProt-1
Q99583
Organism-2
Mouse
SwissProt-2
O08789
背景
The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus.





