FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MLTK
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
91kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MLTK. AA range:701-750
特异性
MLTK Polyclonal Antibody detects endogenous levels of MLTK protein.
基因名称
MLTK
蛋白名称
Mitogen-activated protein kinase kinase kinase MLT
别名
MLTK;ZAK;HCCS4;Mitogen-activated protein kinase kinase kinase MLT;Human cervical cancer suppressor gene 4 protein;HCCS-4;Leucine zipper- and sterile alpha motif-containing kinase;MLK-like mitogen-activated protein triple kinase;Mixe
Organism-1
Human
基因ID-1
51776
SwissProt-1
Q9NYL2
Organism-2
Mouse
基因ID-2
65964
SwissProt-2
Q9ESL4
背景
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Translocates to the nucleus upon ultraviolet B irradiation. .
