- 产品信息
商品描述
靶点-Target
MLK4
反应性
Human,Mouse
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
110kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MAP3KL4. AA range:631-680
特异性
MLK4 Polyclonal Antibody detects endogenous levels of MLK4 protein.
基因名称
MLK4
蛋白名称
Mitogen-activated protein kinase kinase kinase MLK4
别名
MLK4;KIAA1804;Mitogen-activated protein kinase kinase kinase MLK4;Mixed lineage kinase 4
Organism-1
Human
基因ID-1
84451
SwissProt-1
Q5TCX8
Organism-2
Mouse
SwissProt-2
Q8VDG6
背景
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation.,function:Activates the JUN N-terminal pathway.,PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH3 domain.,subunit:Homodimer.,
细胞定位
intracellular,





