FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MLK3
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
93kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MLK3. AA range:640-689
特异性
MLK3 Polyclonal Antibody detects endogenous levels of MLK3 protein.
基因名称
MAP3K11
蛋白名称
Mitogen-activated protein kinase kinase kinase 11
别名
MAP3K11;MLK3;PTK1;SPRK;Mitogen-activated protein kinase kinase kinase 11;Mixed lineage kinase 3;Src-homology 3 domain-containing proline-rich kinase
Organism-1
Human
基因ID-1
4296
SwissProt-1
Q16584
Organism-2
Mouse
基因ID-2
26403
SwissProt-2
Q80XI6
Organism-3
Rat
基因ID-3
309168
SwissProt-3
Q66HA1
背景
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Location is cell cycle dependent.
