- 产品信息
商品描述
靶点-Target
MLK2
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
104kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MAP3K10. AA range:391-440
特异性
MLK2 Polyclonal Antibody detects endogenous levels of MLK2 protein.
基因名称
MAP3K10
蛋白名称
Mitogen-activated protein kinase kinase kinase 10
别名
MAP3K10;MLK2;MST;Mitogen-activated protein kinase kinase kinase 10;Mixed lineage kinase 2;Protein kinase MST
Organism-1
Human
基因ID-1
4294
SwissProt-1
Q02779
Organism-2
Mouse
SwissProt-2
Q66L42
背景
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008],
细胞定位
intracellular,cytoplasm,





