FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MLH1
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
85kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MLH1. AA range:441-490
特异性
MLH1 Polyclonal Antibody detects endogenous levels of MLH1 protein.
基因名称
MLH1
蛋白名称
DNA mismatch repair protein Mlh1
别名
MLH1;COCA2;DNA mismatch repair protein Mlh1;MutL protein homolog 1
Organism-1
Human
基因ID-1
4292
SwissProt-1
P40692
Organism-2
Mouse
基因ID-2
17350
SwissProt-2
Q9JK91
Organism-3
Rat
基因ID-3
81685
SwissProt-3
P97679
背景
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009],
细胞定位
Nucleus . Chromosome . Recruited to chromatin in a MCM9-dependent manner. .
