- 产品信息
商品描述
靶点-Target
MLC-2
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
20kD
推荐稀释比
IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MLC-2. AA range:5-54
特异性
MLC-2 Polyclonal Antibody detects endogenous levels of MLC-2 protein.
基因名称
MYL12A
蛋白名称
Myosin regulatory light chain 12A
别名
MYL12A;MLCB;MRLC3;RLC;Myosin regulatory light chain 12A;MLC-2B;Myosin RLC;Myosin regulatory light chain 2;nonsarcomeric;Myosin regulatory light chain MRLC3;MYL12B;MRLC2;MYLC2B;Myosin regulatory light chain 12B;MLC-2A;MLC-2;M
Organism-1
Human
基因ID-1
10398;10627
SwissProt-1
P19105;O14950;P24844
Organism-2
Mouse
基因ID-2
67938;98932
Organism-3
Rat
基因ID-3
50685;296313
SwissProt-3
P18666;Q64122
背景
This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.[provided by RefSeq, Dec 2014],
细胞定位
stress fiber,cytosol,brush border,myosin complex,myosin II complex,Z disc,apical part of cell,extracellular exosome,





