FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MKP-5
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
52kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from MKP-5 . at AA range: 330-410
特异性
MKP-5 Polyclonal Antibody detects endogenous levels of MKP-5 protein.
基因名称
DUSP10
蛋白名称
Dual specificity protein phosphatase 10
别名
DUSP10;MKP5;Dual specificity protein phosphatase 10;Mitogen-activated protein kinase phosphatase 5;MAP kinase phosphatase 5;MKP-5
Organism-1
Human
基因ID-1
11221
SwissProt-1
Q9Y6W6
Organism-2
Mouse
基因ID-2
63953
SwissProt-2
Q9ESS0
背景
dual specificity phosphatase 10(DUSP10) Homo sapiens Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],
细胞定位
Cytoplasm. Nucleus.
