FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MIF
反应性
Human,Mouse,Rat
应用
IF,WB,IHC,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
12kD
推荐稀释比
IF 1:50-200;WB 1:500-2000;ELISA 1:10000-20000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MIF. AA range:25-74
特异性
MIF Polyclonal Antibody detects endogenous levels of MIF protein.
基因名称
MIF
蛋白名称
Macrophage migration inhibitory factor
别名
MIF;GLIF;MMIF;Macrophage migration inhibitory factor;MIF;Glycosylation-inhibiting factor;GIF;L-dopachrome isomerase;L-dopachrome tautomerase;Phenylpyruvate tautomerase
Organism-1
Human
基因ID-1
4282
SwissProt-1
P14174
Organism-2
Mouse
基因ID-2
17319
SwissProt-2
P34884
Organism-3
Rat
基因ID-3
81683
SwissProt-3
P30904
背景
This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008],
细胞定位
Secreted . Cytoplasm . Does not have a cleavable signal sequence and is secreted via a specialized, non-classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens. .
