- 产品信息
商品描述
靶点-Target
Mi2-β
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
218kD
推荐稀释比
IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CHD4. AA range:571-620
特异性
Mi2-β Polyclonal Antibody detects endogenous levels of Mi2-β protein.
基因名称
CHD4
蛋白名称
Chromodomain-helicase-DNA-binding protein 4
别名
CHD4;Chromodomain-helicase-DNA-binding protein 4;CHD-4;ATP-dependent helicase CHD4;Mi-2 autoantigen 218 kDa protein;Mi2-beta
Organism-1
Human
基因ID-1
1108
SwissProt-1
Q14839
Organism-2
Mouse
基因ID-2
107932
SwissProt-2
Q6PDQ2
背景
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
细胞定位
Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Associates with centrosomes in interphase. .





