FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MGMT
反应性
Human,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
22kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MGMT. AA range:1-50
特异性
MGMT Polyclonal Antibody detects endogenous levels of MGMT protein.
基因名称
MGMT
蛋白名称
Methylated-DNA--protein-cysteine methyltransferase
别名
MGMT;Methylated-DNA--protein-cysteine methyltransferase;6-O-methylguanine-DNA methyltransferase;MGMT;O-6-methylguanine-DNA-alkyltransferase
Organism-1
Human
基因ID-1
4255
SwissProt-1
P16455
Organism-2
Mouse
SwissProt-2
P26187
Organism-3
Rat
基因ID-3
25332
SwissProt-3
P24528
背景
Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015],
细胞定位
Nucleus.
