mGluR5 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614909

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商品描述
  • 靶点-Target

    mGluR5

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    130kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human GRM5. AA range:21-70

  • 特异性

    mGluR5 Polyclonal Antibody detects endogenous levels of mGluR5 protein.

  • 基因名称

    GRM5

  • 蛋白名称

    Metabotropic glutamate receptor 5

  • 别名

    GRM5;GPRC1E;MGLUR5;Metabotropic glutamate receptor 5;mGluR5

  • Organism-1

    Human

  • 基因ID-1

    2915

  • SwissProt-1

    P41594

  • Organism-2

    Mouse

  • 基因ID-2

    108071

  • SwissProt-2

    Q3UVX5

  • Organism-3

    Rat

  • 基因ID-3

    24418

  • SwissProt-3

    P31424

  • 背景

    glutamate metabotropic receptor 5(GRM5) Homo sapiens This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],

  • 细胞定位

    Cell membrane ; Multi-pass membrane protein .