- 产品信息
商品描述
靶点-Target
mGluR5
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GRM5. AA range:21-70
特异性
mGluR5 Polyclonal Antibody detects endogenous levels of mGluR5 protein.
基因名称
GRM5
蛋白名称
Metabotropic glutamate receptor 5
别名
GRM5;GPRC1E;MGLUR5;Metabotropic glutamate receptor 5;mGluR5
Organism-1
Human
基因ID-1
2915
SwissProt-1
P41594
Organism-2
Mouse
基因ID-2
108071
SwissProt-2
Q3UVX5
Organism-3
Rat
基因ID-3
24418
SwissProt-3
P31424
背景
glutamate metabotropic receptor 5(GRM5) Homo sapiens This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
细胞定位
Cell membrane ; Multi-pass membrane protein .





