FGF-2 Polyclonal Antibody
¥680.00
mGluR-2/3 Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2614907
- 产品信息
商品描述
靶点-Target
mGluR-2/3
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
100kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human mGluR2/3. AA range:823-872
特异性
mGluR-2/3 Polyclonal Antibody detects endogenous levels of mGluR-2/3 protein.
基因名称
GRM2
蛋白名称
Metabotropic glutamate receptor 2
别名
GRM2;GPRC1B;MGLUR2;Metabotropic glutamate receptor 2;mGluR2;GRM3;GPRC1C;MGLUR3;Metabotropic glutamate receptor 3;mGluR3
Organism-1
Human
基因ID-1
2912;2913
SwissProt-1
Q14416;Q14832
Organism-2
Mouse
基因ID-2
108068;108069
Organism-3
Rat
基因ID-3
24415;24416
SwissProt-3
P31421;P31422
背景
glutamate metabotropic receptor 2(GRM2) Homo sapiens L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene
细胞定位
Cell membrane; Multi-pass membrane protein. Cell junction, synapse . Cell projection, dendrite .
