FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
mGluR1
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
132kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GRM1. AA range:251-300
特异性
mGluR1 Polyclonal Antibody detects endogenous levels of mGluR1 protein.
基因名称
GRM1
蛋白名称
Metabotropic glutamate receptor 1
别名
GRM1;GPRC1A;MGLUR1;Metabotropic glutamate receptor 1;mGluR1
Organism-1
Human
基因ID-1
2911
SwissProt-1
Q13255
Organism-2
Mouse
基因ID-2
14816
SwissProt-2
P97772
Organism-3
Rat
基因ID-3
24414
SwissProt-3
P23385
背景
glutamate metabotropic receptor 1(GRM1) Homo sapiens This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013],
细胞定位
Cell membrane ; Multi-pass membrane protein .
