Mitofusin-2 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2614904
- 产品信息
商品描述
靶点-Target
Mitofusin-2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
86kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Mfn2. AA range:354-403
特异性
Mfn2 Polyclonal Antibody detects endogenous levels of Mfn2 protein.
基因名称
MFN2
蛋白名称
Mitofusin-2
别名
MFN2;CPRP1;KIAA0214;Mitofusin-2;Transmembrane GTPase MFN2
Organism-1
Human
基因ID-1
9927
SwissProt-1
O95140
Organism-2
Mouse
基因ID-2
170731
SwissProt-2
Q80U63
Organism-3
Rat
SwissProt-3
Q8R500
背景
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion outer membrane ; Multi-pass membrane protein . Colocalizes with BAX during apoptosis. .





