FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Menin
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
67kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MEN1. AA range:181-230
特异性
Menin Polyclonal Antibody detects endogenous levels of Menin protein.
基因名称
MEN1
蛋白名称
Menin
别名
MEN1;SCG2;Menin
Organism-1
Human
基因ID-1
4221
SwissProt-1
O00255
Organism-2
Mouse
基因ID-2
17283
SwissProt-2
O88559
Organism-3
Rat
基因ID-3
29417
SwissProt-3
Q9WVR8
背景
This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008],
细胞定位
Nucleus . Concentrated in nuclear body-like structures. Relocates to the nuclear matrix upon gamma irradiation.
