Melanopsin Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2614897
- 产品信息
商品描述
靶点-Target
Melanopsin
反应性
Human,Rat,Mouse,
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
55kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human OPN4. AA range:429-478
特异性
Melanopsin Polyclonal Antibody detects endogenous levels of Melanopsin protein.
基因名称
OPN4
蛋白名称
Melanopsin
别名
OPN4;MOP;Melanopsin;Opsin-4
Organism-1
Human
基因ID-1
94233
SwissProt-1
Q9UHM6
Organism-2
Mouse
SwissProt-2
Q9QXZ9
背景
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by Ref
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell projection, axon . Cell projection, dendrite . Perikaryon .





