- 产品信息
商品描述
靶点-Target
MEL-1A-R
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
39kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MTR1A. AA range:191-240
特异性
MEL-1A-R Polyclonal Antibody detects endogenous levels of MEL-1A-R protein.
基因名称
MTNR1A
蛋白名称
Melatonin receptor type 1A
别名
MTNR1A;Melatonin receptor type 1A;Mel-1A-R;Mel1a receptor
Organism-1
Human
基因ID-1
4543
SwissProt-1
P48039
Organism-2
Mouse
基因ID-2
17773
SwissProt-2
Q61184
Organism-3
Rat
SwissProt-3
P49218
背景
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Multi-pass membrane protein.





