- 产品信息
商品描述
靶点-Target
ME2
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
65kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ME2. AA range:201-250
特异性
ME2 Polyclonal Antibody detects endogenous levels of ME2 protein.
基因名称
ME2
蛋白名称
NAD-dependent malic enzyme mitochondrial
别名
ME2;NAD-dependent malic enzyme;mitochondrial;NAD-ME;Malic enzyme 2
Organism-1
Human
基因ID-1
4200
SwissProt-1
P23368
Organism-2
Mouse
SwissProt-2
Q99KE1
背景
This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009],
细胞定位
Mitochondrion matrix .





