MCT8 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614865

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商品描述
  • 靶点-Target

    MCT8

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    60kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human SLC16A2. AA range:112-161

  • 特异性

    MCT8 Polyclonal Antibody detects endogenous levels of MCT8 protein.

  • 基因名称

    SLC16A2

  • 蛋白名称

    Monocarboxylate transporter 8

  • 别名

    SLC16A2;MCT8;XPCT;Monocarboxylate transporter 8;MCT 8;Monocarboxylate transporter 7;MCT 7;Solute carrier family 16 member 2;X-linked PEST-containing transporter

  • Organism-1

    Human

  • 基因ID-1

    6567

  • SwissProt-1

    P36021

  • Organism-2

    Mouse

  • 基因ID-2

    20502

  • SwissProt-2

    O70324

  • Organism-3

    Rat

  • 基因ID-3

    259248

  • SwissProt-3

    Q8K1P8

  • 背景

    This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome. [provided by RefSeq, Mar 2012],

  • 细胞定位

    Cell membrane ; Multi-pass membrane protein .