- 产品信息
商品描述
靶点-Target
MCT8
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SLC16A2. AA range:112-161
特异性
MCT8 Polyclonal Antibody detects endogenous levels of MCT8 protein.
基因名称
SLC16A2
蛋白名称
Monocarboxylate transporter 8
别名
SLC16A2;MCT8;XPCT;Monocarboxylate transporter 8;MCT 8;Monocarboxylate transporter 7;MCT 7;Solute carrier family 16 member 2;X-linked PEST-containing transporter
Organism-1
Human
基因ID-1
6567
SwissProt-1
P36021
Organism-2
Mouse
基因ID-2
20502
SwissProt-2
O70324
Organism-3
Rat
基因ID-3
259248
SwissProt-3
Q8K1P8
背景
This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome. [provided by RefSeq, Mar 2012],
细胞定位
Cell membrane ; Multi-pass membrane protein .





