MCT4 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

一键复制产品信息
产品规格:
  • 50μL
  • 100μL
货号:

FAB2614864

  • 产品信息
  • 注意事项
  • 实验验证
  • 产品声明
  • 引用文献
  • 相关产品
  • 文件下载
商品描述
  • 靶点-Target

    MCT4

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    49kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human MOT4. AA range:233-282

  • 特异性

    MCT4 Polyclonal Antibody detects endogenous levels of MCT4 protein.

  • 基因名称

    SLC16A3

  • 蛋白名称

    Monocarboxylate transporter 4

  • 别名

    SLC16A3;MCT4;Monocarboxylate transporter 4;MCT 4;Solute carrier family 16 member 3

  • Organism-1

    Human

  • 基因ID-1

    9123

  • SwissProt-1

    O15427

  • Organism-2

    Mouse

  • 基因ID-2

    80879

  • SwissProt-2

    P57787

  • Organism-3

    Rat

  • 基因ID-3

    80878

  • SwissProt-3

    O35910

  • 背景

    Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008],

  • 细胞定位

    Cell membrane; Multi-pass membrane protein.