- 产品信息
商品描述
靶点-Target
MaxiKβ
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
24kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MaxiKbeta. AA range:70-119
特异性
MaxiKβ Polyclonal Antibody detects endogenous levels of MaxiKβ protein.
基因名称
KCNMB4
蛋白名称
Calcium-activated potassium channel subunit beta-4
别名
KCNMB4;Calcium-activated potassium channel subunit beta-4;BK channel subunit beta-4;BKbeta4;Hbeta4;Calcium-activated potassium channel;subfamily M subunit beta-4;Charybdotoxin receptor subunit beta-4;K;VCA;beta-4;Maxi K channel sub
Organism-1
Human
基因ID-1
27345
SwissProt-1
Q86W47
Organism-2
Mouse
基因ID-2
58802
SwissProt-2
Q9JIN6
Organism-3
Rat
基因ID-3
66016
SwissProt-3
Q9ESK8
背景
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq, Jul 2008],
细胞定位
Membrane; Multi-pass membrane protein.





