MaxiKβ Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614848

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商品描述
  • 靶点-Target

    MaxiKβ

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    24kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human MaxiKbeta. AA range:70-119

  • 特异性

    MaxiKβ Polyclonal Antibody detects endogenous levels of MaxiKβ protein.

  • 基因名称

    KCNMB4

  • 蛋白名称

    Calcium-activated potassium channel subunit beta-4

  • 别名

    KCNMB4;Calcium-activated potassium channel subunit beta-4;BK channel subunit beta-4;BKbeta4;Hbeta4;Calcium-activated potassium channel;subfamily M subunit beta-4;Charybdotoxin receptor subunit beta-4;K;VCA;beta-4;Maxi K channel sub

  • Organism-1

    Human

  • 基因ID-1

    27345

  • SwissProt-1

    Q86W47

  • Organism-2

    Mouse

  • 基因ID-2

    58802

  • SwissProt-2

    Q9JIN6

  • Organism-3

    Rat

  • 基因ID-3

    66016

  • SwissProt-3

    Q9ESK8

  • 背景

    MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Membrane; Multi-pass membrane protein.