Matriptase Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614846

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商品描述
  • 靶点-Target

    Matriptase

  • 反应性

    Human,Mouse

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    95kD

  • 推荐稀释比

    WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human ST14. AA range:10-59

  • 特异性

    Matriptase Polyclonal Antibody detects endogenous levels of Matriptase protein.

  • 基因名称

    ST14

  • 蛋白名称

    Suppressor of tumorigenicity 14 protein

  • 别名

    ST14;PRSS14;SNC19;TADG15;Suppressor of tumorigenicity 14 protein;Matriptase;Membrane-type serine protease 1;MT-SP1;Prostamin;Serine protease 14;Serine protease TADG-15;Tumor-associated differentially-expressed gene 15 protein

  • Organism-1

    Human

  • 基因ID-1

    6768

  • SwissProt-1

    Q9Y5Y6

  • Organism-2

    Mouse

  • SwissProt-2

    P56677

  • 背景

    The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Membrane ; Single-pass type II membrane protein .