Matriptase Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2614846
- 产品信息
商品描述
靶点-Target
Matriptase
反应性
Human,Mouse
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
95kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ST14. AA range:10-59
特异性
Matriptase Polyclonal Antibody detects endogenous levels of Matriptase protein.
基因名称
ST14
蛋白名称
Suppressor of tumorigenicity 14 protein
别名
ST14;PRSS14;SNC19;TADG15;Suppressor of tumorigenicity 14 protein;Matriptase;Membrane-type serine protease 1;MT-SP1;Prostamin;Serine protease 14;Serine protease TADG-15;Tumor-associated differentially-expressed gene 15 protein
Organism-1
Human
基因ID-1
6768
SwissProt-1
Q9Y5Y6
Organism-2
Mouse
SwissProt-2
P56677
背景
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008],
细胞定位
Membrane ; Single-pass type II membrane protein .





