- 产品信息
商品描述
靶点-Target
MASP-2
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
75kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MASP2. AA range:227-276
特异性
MASP-2 Polyclonal Antibody detects endogenous levels of MASP-2 protein.
基因名称
MASP2
蛋白名称
Mannan-binding lectin serine protease 2
别名
MASP2;Mannan-binding lectin serine protease 2;MBL-associated serine protease 2;Mannose-binding protein-associated serine protease 2;MASP-2
Organism-1
Human
基因ID-1
10747
SwissProt-1
O00187
Organism-2
Mouse
SwissProt-2
Q91WP0
背景
mannan binding lectin serine peptidase 2(MASP2) Homo sapiens This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016],
细胞定位
Secreted.





