FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MARCH5
反应性
Human,Mouse,Rat
应用
IF,WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
37kD
推荐稀释比
WB 1:500-2000;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MARCH5. AA range:21-70
特异性
MARCH5 Polyclonal Antibody detects endogenous levels of 40607 protein.
基因名称
MARCH5
蛋白名称
E3 ubiquitin-protein ligase MARCH5
别名
MARCH5;RNF153;E3 ubiquitin-protein ligase MARCH5;Membrane-associated RING finger protein 5;Membrane-associated RING-CH protein V;MARCH-V;Mitochondrial ubiquitin ligase;MITOL;RING finger protein 153
Organism-1
Human
基因ID-1
54708
SwissProt-1
Q9NX47
Organism-2
Mouse
基因ID-2
69104
SwissProt-2
Q3KNM2
背景
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM, Mar 2008],
细胞定位
Mitochondrion outer membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Authors show that the protein can be detected in endoplasmic reticulum (PubMed:14722266). Authors (PubMed:16874301) show its presence only in mitochondria (PubMed:16874301). .
