FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MARCH4
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
46kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MARCH4. AA range:301-350
特异性
MARCH4 Polyclonal Antibody detects endogenous levels of 40606 protein.
基因名称
MARCH4
蛋白名称
E3 ubiquitin-protein ligase MARCH4
别名
MARCH4;KIAA1399;RNF174;E3 ubiquitin-protein ligase MARCH4;Membrane-associated RING finger protein 4;Membrane-associated RING-CH protein IV;MARCH-IV;RING finger protein 174
Organism-1
Human
基因ID-1
57574
SwissProt-1
Q9P2E8
Organism-2
Mouse
基因ID-2
381270
SwissProt-2
Q80TE3
背景
MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010],
细胞定位
Golgi apparatus membrane ; Multi-pass membrane protein .
