FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MARCH2
反应性
Human,Rat,Mouse,
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
27kD
推荐稀释比
IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MARCH2. AA range:191-240
特异性
MARCH2 Polyclonal Antibody detects endogenous levels of 40604 protein.
基因名称
MARCH2
蛋白名称
E3 ubiquitin-protein ligase MARCH2
别名
MARCH2;RNF172;HSPC240;E3 ubiquitin-protein ligase MARCH2;Membrane-associated RING finger protein 2;Membrane-associated RING-CH protein II;MARCH-II;RING finger protein 172
Organism-1
Human
基因ID-1
51257
SwissProt-1
Q9P0N8
Organism-2
Mouse
SwissProt-2
Q99M02
背景
MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Cytoplasm . Cell membrane ; Multi-pass membrane protein .
